Treatment of Rheumatoid Arthritis Using Combination DMARD Therapy with Salazosulfapyridine

Autor:	Iwao Yanagida, Kensuke Yamanaka, Tsuyoshi Matsuura, Akio Inoue, Seiichiro Mita, Masao Hiromatsu, Sanshiro Hashimoto
Rok vydání:	1996
Předmět:	musculoskeletal diseases medicine.medical_specialty Combination therapy business.industry Incidence (epidemiology) medicine.disease FAVORABLE RESPONSE immune system diseases Rheumatoid arthritis Internal medicine Dmard therapy medicine skin and connective tissue diseases business
Zdroj:	Orthopedics & Traumatology. 45:690-694
ISSN:	1349-4333 0037-1033
DOI:	10.5035/nishiseisai.45.690
Popis:	Fifty-three patients with rheumatoid arthritis were evaluated for the effect of combination DMARD therapy. Various combinations of DMARDs for the treatment of active RA were used, although in this study about 80% of RA patients were treated using combination DMARD therapy with salazosulfapyridine(SASP). The combination therapy with SASP was maintained for more than 2 years in 12 patients (21.8%). During the first 6 months of combination therapy 50.9% (28/55) of the patients had an overall favorable response. The incidence of side effects was 23.6% (13/55), but this was almost the same as that reported for single DMARD therapy. The results revealed that combination DMARD therapy with SASP is an effective therapy to use before changing from one DMARD to another.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f478414be94bbd8337719a00d31da5f6 https://doi.org/10.5035/nishiseisai.45.690 Zobrazit plný text záznamu