Partial agonists of dopamine receptors: receptor theory and the dopamine hypothesis of psychosis

Autor:	Jonathan Pimm, John Cookson
Rok vydání:	2021
Předmět:	Psychiatry and Mental health Psychosis business.industry Dopamine receptor Medicine business medicine.disease Receptor theory Partial agonist Neuroscience Dopamine hypothesis of schizophrenia
Zdroj:	BJPsych Advances. 29:141-144
ISSN:	2056-4686 2056-4678
DOI:	10.1192/bja.2021.39
Popis:	SUMMARYThis article discusses dopamine partial agonism, which is the main mechanism of action of the psychiatric drugs aripiprazole, brexpiprazole and cariprazine. It outlines the principles of receptor theory and the structure of dopamine receptors; characterises agonists, antagonists and partial agonists; and summarises the dopamine hypothesis of psychosis and the role of dopamine and serotonin in depression.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f467bbc56f9b9855ebb7c621f7d81386 https://doi.org/10.1192/bja.2021.39 Zobrazit plný text záznamu