SELECTIVE EFFECTS OF GROWTH HORMONE ON RATS FED A TRYPTOPHAN-LOW DIET1

Autor:	Sol Bernick, Lucien A. Bavetta, Benjamin H. Ershoff
Rok vydání:	1956
Předmět:	Vitamin medicine.medical_specialty Low protein Biology Pyridoxine Growth hormone treatment chemistry.chemical_compound Endocrinology medicine.anatomical_structure Anterior pituitary chemistry Casein Internal medicine Pantothenic acid medicine Thiamine medicine.drug
Zdroj:	Endocrinology. 58:701-707
ISSN:	1945-7170 0013-7227
DOI:	10.1210/endo-58-6-701
Popis:	CONSIDERABLE data are available indicating that growth hormone administration will not promote a weight increment in animals that are nutritionally deficient. Thus growth-promoting extracts of the anterior pituitary failed to promote a gain in body weight in rats deficient in vitamin A (Margitay-Becht and AYallner, 1937; Ershoff and Deuel; 1945), thiamine (Simpson and Evans, 1944), the essential fatty acids (Deuel et al., 1950), pantothenic acid (Lotspeich, 1950; Beare et al., 1954), pyridoxine (Beare et al., 1953), choline (Hall and Bieri, 1953) or riboflavin (Beare et al., 1954). Similarly growth hormone failed to promote an increment in body weight in rats fed a low protein (6% casein) diet (Gordan et al., 1947, 1948). Supplementing the above diet with dl-methionine or increasing the casein content to a minimum of 12% of the ration resulted, however, in a significant weight increment following growth hormone treatment.
Databáze:	OpenAIRE
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