ChemInform Abstract: An Efficient Method for the Synthesis of Substituted TosMIC Precursors

Autor:	Joseph Sisko, Peter W. Sheldrake, Mark Mellinger, Neil H. Baine
Rok vydání:	2010
Předmět:	chemistry.chemical_compound General method Chemistry Reagent TosMIC Organic chemistry General Medicine Formamides Combinatorial chemistry
Zdroj:	ChemInform. 28
ISSN:	0931-7597
DOI:	10.1002/chin.199707114
Popis:	Substituted tosylmethyl isocyanides (TosMICs) are useful reagents for which no general method of preparation is available. We describe here a high-yielding method for the synthesis of substituted tosylmethyl formamides, which are readily converted to the corresponding isocyanides.
Databáze:	OpenAIRE
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