| Popis: |
Background: International and national New Zealand (NZ) research has identified women of South Asian ethnicity at increased risk of perinatal mortality, in particular stillbirth, with calls for increased perinatal research among this ethnic group. We aimed to analyse differences in pregnancy outcomes and associated risk factors between South Asian, Māori, Pacific, and New Zealand European women in Aotearoa NZ, with a focus on women of South Asian ethnicity, to ultimately understand the distinctive pathways leading to adverse events. Methods: Clinical data from perinatal deaths between 2008 and 2017 were provided by the NZ Perinatal and Maternal Mortality Review Committee (PMMRC), while national maternity and neonatal data, and singleton birth records from the same decade were linked using the Statistics NZ Integrated Data Infrastructure for all births. Pregnancy outcomes and risk factors for stillbirth and neonatal death were compared between ethnicities with adjustment for pre-specified risk factors. Results: Women of South Asian ethnicity were at increased risk of stillbirth (aOR 1.51, 95%CI 1.29-1.77), and neonatal death (aOR 1.51, 95%CI 1.17-1.92), compared to NZ European. The highest perinatal related mortality rates among South Asian women were between 20-22 weeks gestation (at 1.3 and 1.1/1,000 ongoing pregnancies; pConclusions: Women of South Asian ethnicity in Aotearoa NZ were at increased risk of stillbirth and neonatal death compared to NZ European women. Metabolic-related factors may contribute to adverse pregnancy outcomes in South Asian mothers. |
