Microwave-Enhanced Greener Synthesis of Indazoles via Nitrenes

Autor:	Deepu Varughese, Maghar S. Manhas, Ajay K. Bose
Rok vydání:	2007
Předmět:	Microwave chemistry Chemistry Nitrene Microwave irradiation Nitro Organic chemistry chemistry.chemical_element General Medicine Photochemistry Nitrogen Microwave
Zdroj:	ChemInform. 38
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200701120
Popis:	Non-traditional methods (grinding, water-based biphasic reactions, microwave chemistry) were used for the preparation of Schiff bases from several amines and 2-nitrobenzaldehydes. These nitro compounds were allowed to react with triethyl phosphite under microwave irradiation for the generation of nitrenes that underwent insertion reactions to form indazoles. This procedure constitutes an energy-efficient, greener chemistry version of the Cadogan reaction for nitrene-based formation of nitrogen heterocycles.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f437efd41ab6b36f1732a5d4af1f6482 https://doi.org/10.1002/chin.200701120 Zobrazit plný text záznamu Plný text