MO578OSTEOCALCIN AND VASCULAR CALCIFICATION IN HEMODIALYSIS PATIENTS: AN OBSERVATIONAL COHORT STUDY

Autor:	Nagwa I. Okaily, Ahmed Mohamed Saadeldin Salama, Hesham Kamal Habeeb Keryakos, Mariam Asaad Yacoub Boulis
Rok vydání:	2021
Předmět:	Transplantation medicine.medical_specialty business.industry medicine.medical_treatment medicine.disease Nephrology Diabetes mellitus Internal medicine Vitamin K deficiency Medicine Hemodialysis business Vascular calcification Cohort study
Zdroj:	Nephrology Dialysis Transplantation. 36
ISSN:	1460-2385 0931-0509
DOI:	10.1093/ndt/gfab086.0016
Popis:	Background and Aims Vascular calcification contributes to morbidity and mortality in patients with ESRD on maintenance hemodialysis. to study the relationship between osteocalcin and vascular calcification. Method 160 patients with ESRD on maintenance hemodialysis and 60 age-and sex-matched healthy controls were recruited. Serum vitamin K2 and osteocalcin both intact and undercarboxylated were measured. Transthoracic echocardiography was done for valvular calcification and thickening, and carotid duplex was done for carotid intimal medial calcification and thickening. Results Hemodialysis patients have higher median serum vitamin K2 (p Conclusion Functional vitamin K deficiency is present in maintenance hemodialysis patients and serum osteocalcin is not associated with cardiovascular calcification.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f423072af22c49301fb7c87afbe58fbd https://doi.org/10.1093/ndt/gfab086.0016 Zobrazit plný text záznamu