Biological activities of the essential oil from the leaves ofXylopia laevigata(Annonaceae)

Autor: Marcos José Salvador, Thanany Brasil da Silva, Mario Antonio Navarro da Silva, Leociley R. A. Menezes, Luis Henrique Gonzaga Ribeiro, Lígia Moraes Barizon de Souza, João Carvalho, Emmanoel V. Costa, Carlos Siqueira, Fernanda Ramos Gadelha
Rok vydání: 2013
Předmět:
Zdroj: Journal of Essential Oil Research. 25:179-185
ISSN: 2163-8152
1041-2905
Popis: The essential oil from the leaves of Xylopia laevigata was obtained by hydrodistillation and analyzed by gas chromatography/mass spectrometry (GC/MS) and GC/flame ionization detector (GC/FID). Thirty-six compounds representing 97.48% of the crude essential oil were identified. The major compounds identified were -muurolene (17.99%), -cadinene (13.45%), germacrene D (9.09%), bicyclogermacrene (7.00%), -copaene (5.98%), and (E)-caryophyllene (5.43%). The biological activities of the essential oil against Trypanosoma cruzi epimastigote forms, yeast, bacteria, Aedes aegypti larvae, antioxidant properties and antiproliferative activity against tumor cell lines were investigated. The essential oil showed trypanocidal activity with IC50 value of 93.9±2.6 μg/mL. For antibacterial and antifungal activities, the best results were observed against Staphylococcus aureus (ATCC14458), Staphylococcus epidermidis (ATCC1228) and Candida tropicalis (ATCC 157), all with a minimal inhibitory concentration value of 100 μg/mL....
Databáze: OpenAIRE
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