Preparation of dextran-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) copolymer and its micellar characteristics

Autor:	Yan Wu, Hongxia Gao, Tiewei Wang, Mingjun Li, Aijun Zeng, Qing Xu
Rok vydání:	2010
Předmět:	Aqueous solution Polymers and Plastics Organic Chemistry technology industry and agriculture Carbon-13 NMR Micelle Gel permeation chromatography chemistry.chemical_compound Dextran chemistry Dynamic light scattering Materials Chemistry Proton NMR Copolymer Organic chemistry Nuclear chemistry
Zdroj:	Carbohydrate Polymers. 80:303-307
ISSN:	0144-8617
DOI:	10.1016/j.carbpol.2009.10.068
Popis:	A novel amphiphilic copolymer based on dextran and 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) was synthesized and characterized by 1 H NMR, 13 C NMR and 31 P NMR spectra. Their molecular weights were determined by gel permeation chromatography (GPC). The molecular weights range from 13 kDa to 21 kDa in the molar ratio of 3:1–10:1 (DPPE/activated dextran). Its micellar characteristics in aqueous solution were investigated by fluorescence technique, transmission electron microscopy (TEM) and dynamic light scattering (DLS). It was found that dextran/DPPE copolymer could self-assembly in water into spherical micelles with the diameters ranged from 30 to 60 nm in the absence of organic solvent or surfactant.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f3fe296b576249b40052da7bac7afd81 https://doi.org/10.1016/j.carbpol.2009.10.068 Zobrazit plný text záznamu Full Text from ScienceDirect