Natural Antibodies to Human Lymphocytes in Murine Strains 2 3
Autor: | Soldano Ferrone, K. K. Mittal, M. A. Pellegrino |
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Rok vydání: | 1976 |
Předmět: | |
Zdroj: | JNCI: Journal of the National Cancer Institute. 56:75-78 |
ISSN: | 1460-2105 0027-8874 |
Popis: | Murine strains vary greatly in their content of natural antibodies to human lymphocytes; sera from NZB, B10.BR/TSn, DBA/J, and B10.S mice reacted with more than 90% of the panel of human lymphocytes, yet those from other strains did not react. These levels of natural antibodies to human lymphocytes did not correlate with the H-2 type of mice, but appeared to be a dominant character with incomplete penetrance. Since sera from germfree mice also contained natural antibodies to human lymphocytes, their formation was not influenced substantially by bacteria. |
Databáze: | OpenAIRE |
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