Natural Antibodies to Human Lymphocytes in Murine Strains 2 3

Autor:	Soldano Ferrone, K. K. Mittal, M. A. Pellegrino
Rok vydání:	1976
Předmět:	Cancer Research medicine.anatomical_structure Oncology Lymphocyte medicine biology.protein Biology Antibody biology.organism_classification Penetrance Virology Bacteria Microbiology
Zdroj:	JNCI: Journal of the National Cancer Institute. 56:75-78
ISSN:	1460-2105 0027-8874
Popis:	Murine strains vary greatly in their content of natural antibodies to human lymphocytes; sera from NZB, B10.BR/TSn, DBA/J, and B10.S mice reacted with more than 90% of the panel of human lymphocytes, yet those from other strains did not react. These levels of natural antibodies to human lymphocytes did not correlate with the H-2 type of mice, but appeared to be a dominant character with incomplete penetrance. Since sera from germfree mice also contained natural antibodies to human lymphocytes, their formation was not influenced substantially by bacteria.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f3fa09d2090e67069bb0ebda10a1e8c8 https://doi.org/10.1093/jnci/56.1.75 Zobrazit plný text záznamu