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Based on the homeostatic model assessand lower glucose metabolism in this “Insulin resistance and hyperglycemia ment, increased peripheral insulin resislobe was associated with worse immeare related conditions, and hyperglycetance was significantly associated with diate and delayed memory performance mia, even in the prediabetic range, is decreased glucose metabolism, both factors. “This finding provides a potenassociated with a significantly increased globally and in large areas of the frontial link between insulin resistance and risk for later development of demental, lateral parietal, and medial and latcognitive decline,” they wrote. tia,” they noted. eral temporal lobes, Dr. Willette and his The findings also support results The investigators reported no relevant associates found. from previous studies of older adults conflicts of interest. CfA Insulin resistance and lower glucose that have linked insulin resistance, uptake were especially robustly associhyperglycemia, and diabetes melliAmy Karon is a Frontline Medical News ated in the left medial temporal lobe, tus to hypometabolism on FDG-PET. freelance writer based in Albuquerque, NM. |
