Correlations between the pharmacokinetics and dynamics of pharmacological effects of bromantane

Autor:	A. S. Losev, S. V. Krapivin, I. S. Morozov, Svetlana Alexandrovna Sergeeva
Rok vydání:	1995
Předmět:	Chemistry Dynamics (mechanics) Target tissue General Medicine General Biochemistry Genetics and Molecular Biology Correlation Electrophysiology chemistry.chemical_compound Pharmacokinetics Biophysics Bromantane Neuroscience Organism Mathematical correlation
Zdroj:	Bulletin of Experimental Biology and Medicine. 119:297-300
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf02445841
Popis:	It is shown that there is a mathematical correlation between an integral characteristic of activity of the organism (the capacity for work), electrophysiological indexes of functioning of the brain structures, and the concentration of a novel derivative of 2-aminoadamantane, bromantane, in the brain. The nature of the correlation between integral characteristics of the organism studied on different levels is found to change depending on the time elapsed from the administration of the preparation and on its concentration in the blood or target tissue.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f3ebe075958d273243d330738207ca8b https://doi.org/10.1007/bf02445841 Zobrazit plný text záznamu Full text from SpringerLink