EFFECT OF DURUM WHEAT BRAN ON GLUCOSE AND LIPID METABOLISM IN DIABETIC RATS

Autor: Kadour Sennous, Louiza Tarfaoui, Abdelkrim Benalia, Fafa Boukhatmi, Noreddine Menadi, Samira Meziani, Imene Bekhaled, Mohamed Zairi, Abassia Demmouche
Rok vydání: 2020
Předmět:
Zdroj: Journal of Drug Delivery and Therapeutics. 10:30-34
ISSN: 2250-1177
DOI: 10.22270/jddt.v10i2-s.4000
Popis: Introduction.Durum wheat bran is obtained from wheat milling, it’s considered as an excellent source of insoluble dietary fibre. Objective. The aim of this paper was to evaluate the effect of wheat bran (WB) on glucose and lipid metabolism in normal and diabetic rats. Materials and Methods. Twenty-four female rats of "Wistar" were divided into four groups each containing six rats. The first group (NCR) was fed by a control diet while the second group (NCRE) was fed by the experimental diet based on durum wheat bran. For the third and fourth group after streptozotocin (STZ) injection, they were fed by a control diet (DCR) and experimental diet (DRE) respectively. The Blood Glucose (g/L) and weight (g) of these groups was measured at the end of each week for a period of four weeks, the serum lipid parameters in the fasting condition, such as TC, TG, LDL-C and HDL-C were evaluated at the end of the experience. Results. WB was high in dietary fibre (41%). The results show a significant decrease in blood glucose ( p
Databáze: OpenAIRE