Taquicardia ventricular y QT largo asociados a la administración de claritromicina en un paciente afectado de infección por el VIH

Autor: Esteban Ribera, Nuria Vallejo Camazón, Jordi Soler Soler, Dolors Rodríguez Pardo, Antonio Sánchez Hidalgo, María Pilar Tornos Mas
Rok vydání: 2002
Předmět:
Zdroj: Revista Española de Cardiología. 55:878-881
ISSN: 0300-8932
Popis: Prolongation of the QT interval is associated with a high risk of serious ventricular tachyarrhythmias, usually torsade de pointes (TdP) polymorphic ventricular tachycardia, although monomorphic ventricular tachycardia may also develop. Both congenital and acquired forms have been reported, acquired forms being much more prevalent. An association between human immunodeficiency virus (HIV) infection and a higher rate of dilated cardiomyopathy has also been recognized. The severity of immunodeficiency seems to influence both the incidence and severity of cardiomyopathy. A higher prevalence of QT prolongation has been reported among hospitalized HIV-positive patients with HIV infection, possibly related to drugs prescribed for such patients or to an acquired form of long QT syndrome arising from HIV infection. We report a case of QT prolongation and development of ventricular arrhythmia in one HIV patient that started with intravenous clarithromycin and cotrimoxazole therapy.
Databáze: OpenAIRE