Copper-catalyzed conjugate addition of trialkylaluminium to α,β-unsaturated carbonyl compounds

Autor:	Klaus Nickisch, Harribert Neh, Jürgen Westermann, Steffen Flemming, Jazid Kabbara
Rok vydání:	1995
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Hydrocarbon Chemistry Reagent Organic Chemistry Drug Discovery Copper catalyzed Organic chemistry Trimethylaluminium Biochemistry Conjugate
Zdroj:	Tetrahedron. 51:743-754
ISSN:	0040-4020
DOI:	10.1016/0040-4020(94)00975-z
Popis:	The Michael-type reaction of copper-catalyzed trialkylaluminium reagents with α,β-unsaturated carbonyl compounds is a useful and simple procedure for the transfer of hydrocarbon substituents. The scope of this process and the effect of chlorotrimethylsilane as additive were investigated. Preparatively useful results were generally obtained for enones even with higher organoaluminium reagents, whereas the reaction with α,β-unsaturated aldehydes was limited to the use of trimethylaluminium.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f3c9afb7ee99bd3147635922334bf7fe https://doi.org/10.1016/0040-4020(94)00975-z Zobrazit plný text záznamu Full Text from ScienceDirect