| Autor: |
Khan Mahmood Hasan, Ullah, Asif Rahmat, Haque Ziaul, S.M., Tanveer, Ahmad, Chakraborty Soumen, Reazur, Rahman, Nahar Samsun, Shafique, A.M., Poppy, Bala, Aparajita, Karim, Bhuiyan Azfar, H., Shamsul, Alam, Nighat, Islam, Mohd, Rahman Ziaur, Siddique Atique Bin, Intekhab, Yusuf, Tanbir Hossain, A., Zahidul Haque Md., Choudhary Walid Mohammad Mujib, Das Anjan Kumar |
| Rok vydání: |
2021 |
| Předmět: |
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| DOI: |
10.24412/2701-8369-2021-17-15-23 |
| Popis: |
Background: Coronary heart disease (CHD) is the single most important cause of death. Diagnosing ACS is important because the diagnosis triggers both triage and management. Cardiac Troponin-I (cTnI) known to be a very sensitive and specific marker for extent of coronary artery involvement. The objective of the Study: The study aimed to determine the correlation of extent of coronary artery disease (CAD) with elevated syntax score &Troponin – I level in nonST elevated MI (NSTEMI). Methods: This cross-sectional analytical study was conducted from July 2019 to June 2020 in the Department of Cardiology, United Hospital Limited. Total 230 first attack of NSTEMI patients was included in the study. All patients underwent coronary angiography in United Hospital Limited. Single, double or triple vessel CAD were considered for extent of CAD& syntax score ≤22 as low, 2332 as intermediate & ≥33 were considered as high. The sample population was divided into two groups: Group–I: Patients with first attack of NSTEMI with Troponin-I level ≤6.6 ng/ml. Group–II: Patients with first attack of NSTEMI with Troponin-I level ≥6.6 ng/ml. Association between cTnI levels and CAD extent & severity were observed statistically.Results:Out of 230 patientsof Group-I, majority (36%) had double& mean syntax score was 24.16±5.84, then 30.6% had triple vessel with mean syntax score was 34.70±8.59& the remaining had single vessel CAD with mean syntax score 14.15±5.06, whereas in patients of Group II, most patients (46.2%) had triple vesselwith mean syntax score was 38.50±7.95, then 31.1% had double with mean syntax score was 24.70±8.59& the rest had single vessel CADwith mean syntax score 18.90±9.85. The results indicated statistically significant association between the cTnI levels and triple vessel CAD with highest syntax score (p = 0.04). Our study discovered that increased Troponin-I level over 6.6 ng/ml & elevated syntax score were a very sensitive and specific for CAD extension& severity. Conclusion: The study enabled us to conclude that, higher cTnI levels & syntax score are associated with an increased extension & severity of CAD. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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