Cannabinoids stimulate and inhibit testosterone production and
| Autor: | D. Mayfield, Andrzej Bartke, S. Dalterio |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
medicine.medical_specialty
organic chemicals Testosterone (patch) General Medicine Pharmacology Biology Inhibitory postsynaptic potential General Biochemistry Genetics and Molecular Biology In vitro chemistry.chemical_compound Endocrinology chemistry In vivo Internal medicine mental disorders Cannabinol medicine General Pharmacology Toxicology and Pharmaceutics Cannabidiol medicine.drug |
| Zdroj: | Life Sciences. 32:605-612 |
| ISSN: | 0024-3205 |
| DOI: | 10.1016/0024-3205(83)90205-9 |
| Popis: | The major psychoactive Δ9-tetrahydrocannabinol (THC) and the non-psychoactive cannabinol (CBN) of cannabidiol (CBD) can both stimulate and inhibit testicular testosterone (T) production in vitro and in vivo . At nanomolar concentrations, these cannabinoids stimulate T production by decapsulated mouse testes while, in micromolar amounts, the effects are markedly inhibitory. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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