Thyroidal Action of Synthetic Thyroprotein
| Autor: | Charles W. Turner, E. P. Reineke |
|---|---|
| Rok vydání: | 1943 |
| Předmět: | |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 3:1-6 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-3-1-1 |
| Popis: | DURING the past several years marked progress has been made in the production of synthetic thyroproteins with high physiologic activity. As the result of recent experiments in our laboratory a prodecure has been worked out whereby a product can be obtained which has several-fold the thyroidal activity of desiccated thyroid. While the primary objective of this work was to produce thyroidal material at a cost sufficiently low to warrant its use in feeding domestic animals, it would appear that with the attainment of that objective, a synthetic thyroprotein has been formed which may have important clinical uses not only because of the marked reduction in cost which would be possible, but also because of the uniform potency that would result from standardization of the manufacturing procedure and the biologic assay of large batches of material. The purpose of this paper is to review briefly the history of the progress made in producing synthetic thyroproteins and to call to the attention of experimental clini... |
| Databáze: | OpenAIRE |
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