Effect of Intraportal Glucose Infusion on Hepatic Glycogen Content and Degradation, and Outcome of Liver Transplantation R. CYWES, P. D. GREIG, J. R. SANABRIA, ET AL Annals of Surgery 216:235-247, 1992

Autor: W. Scott Helton
Rok vydání: 1993
Předmět:
Zdroj: Journal of Parenteral and Enteral Nutrition. 17:192-193
ISSN: 1941-2444
0148-6071
Popis: The authors conducted a prospective, randomized study to investigate the effects of an intraportal glucose-insulin infusion during the donor operation for ortho-topic human liver transplantation on hepatic glycogen deposition before cold preservation as well as on hepatic glycogen utilization and liver function after transplantation. Control donors received no special treatment, whereas donors in the experimental group received an infusion of 20% dextrose containing 20 mEq of potassium chloride and 100 IU of Humulin (Eli Lilly, Indianapolis, IN) via the inferior mesenteric vein initiated at the beginning of the donor operation. The infusion rate was started at 10 mL/kg per hour for 6 minutes. Then another 100 IU of Humulin was added to the remaining solution and the infusion rate halved to 5 mL/kg per hour throughout the remainder of the procedure until the time of vascular cross clamping. Arterial blood glucose concentrations were monitored every 15 minutes by glucometer and maintained between 12 and 14 ...
Databáze: OpenAIRE
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