Thrombophilia: Some recent advances in understanding

Autor:	C M James
Rok vydání:	1995
Předmět:	medicine.medical_specialty medicine.drug_class business.industry Anticoagulant General Medicine Thrombophilia medicine.disease Thrombosis Recurrent thromboembolism medicine Family history Activated protein C resistance Intensive care medicine business
Zdroj:	Journal of The Royal Naval Medical Service. 81:203-206
ISSN:	2634-4920 0035-9033
DOI:	10.1136/jrnms-81-203
Popis:	Thrombophilia is a term with many definitions although the majority include criteria such as thrombosis under the age of 45; recurrent thromboembolism and a positive family history. It reflects a disturbance in the normal delicate balance between pro- and anti-coagulation such as to favour inappropriate thrombosis. This review concentrates on the newly described phenomenon of activated protein C resistance while reviewing the natural anticoagulant system. It will also briefly examine the indications for ‘thrombophilia’ screening and the implications for individuals found to have an abnormality of their natural anticoagulants.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f379e15019b84beba4a74c345267964a https://doi.org/10.1136/jrnms-81-203 Zobrazit plný text záznamu