The Value of Trabecular Bone Score in Patients with Rheumatic Diseases
| Autor: | Maxim Aleksandrovich Korolev, Yuliya B. Ubshaeva, Konstantin I. Kolpakov |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Ankylosing spondylitis
medicine.medical_specialty medicine.diagnostic_test business.industry Osteoporosis General Medicine medicine.disease Bone tissue Rheumatology Trabecular bone Trabecular bone score medicine.anatomical_structure Internal medicine medicine In patient business Dual-energy X-ray absorptiometry |
| Zdroj: | Annals of the Russian academy of medical sciences. 76:402-411 |
| ISSN: | 2414-3545 0869-6047 |
| Popis: | Background. Trabecular bone score obtained by lumbar spine Dual-energy X-ray Absorptiometry is a novel and insufficiently explored instrument of accessing trabecular bone quality. One of its promising applications is early diagnostics of osteoporosis (OP) before fragility fractures appear. Meanwhile most of systemic inflammatory rheumatic diseases affect bone tissue either directly and indirectly by glucocorticoids consumption. Both factors potentiate OP development and can influence the trabecular bone score. Aims — to evaluate the possibilities of trabecular bone score using in rheumatology. Materials and Methods. Data analysis of domestic and foreign scientific publications. Results and Discussion. Authors of analyzed publications note stable association of low trabecular bone score with vertebral fractures, its correlation with local inflammatory markers in lumbar spine and ankylosing spondylitis structural progression. In most studies trabecular bone score do not have association with systemic inflammatory activity and treatment. Conclusion. Trabecular bone score is effective in OP diagnostics in rheumatic patients, evaluation of local inflammatory activity in the lumbar spine and structural progression of ankylosing spondylitis. |
| Databáze: | OpenAIRE |
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