ChemInform Abstract: Synthesis and Anthelminthic Evaluation of 2-Amidino-1,3,4-oxa- and 1,3, 4-Thiadiazoles, Structurally Related to Tetramisole

Autor:	Marc Payard, M. Bonnafous, R. Caujolle, Christian Bories, P. R. Loiseau, Philippe M. Loiseau, P. Gayral
Rok vydání:	2010
Předmět:	Rhabditis biology Stereochemistry Chemistry Intestinal parasite General Medicine medicine.disease_cause biology.organism_classification In vitro Nematode Biochemistry Thiadiazoles medicine Nippostrongylus brasiliensis
Zdroj:	ChemInform. 22
ISSN:	0931-7597
DOI:	10.1002/chin.199112214
Popis:	N-(1,3,4-thiadiazol-2-yl) 1a-1k and N-(1,3,4-oxadiazol-2-yl-) amidines 2a-2g, N-(1,3-thiazol-2-yl) 3a, 3b and N-(1,3-benzothiazol-2-yl-)amidines 4a, 4b were synthesized and tested as anthelminthics, in vitro, against a free nematode (Rhabditis pseudoelongata), against infecting larvae of an intestinal parasite of rats (Nippostrongylus brasiliensis) and against infecting larvae of a filaria (Molinema dessetae).
Databáze:	OpenAIRE
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