| Autor: |
Shruti Ghosh, Nimai Chandra Saha, Ritwick Bhattacharya, Sharmistha Medda, Sarmila Pal |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
International Journal for Research in Applied Science and Engineering Technology. 10:1090-1101 |
| ISSN: |
2321-9653 |
| DOI: |
10.22214/ijraset.2022.47561 |
| Popis: |
The present study aimed to assess the acute toxicity of Lauryl alcohol ethoxylate (LAE) and its sublethal effects on oxidative stress enzymes in Tubifex tubifex, a benthic oligochaete worm. The results indicated that the 96-hour median lethal concentration (LC50) of LAE is 0.77 mg/l for Tubifex tubifex. The model fit performance depicted that GUTS-SD model can better predict the survival rate of Tubifex tubifex. Sublethal concentrations of LAE (10% and 20% of the 96h LC50) significantly altered the oxidative stress enzymes. Reduced glutathione (GSH), glutathione S-transferase (GST), and glutathione peroxidase (GPx) all displayed a significant initial increase followed by a subsequent decline, whereas catalase (CAT) activity and malondialdehyde (MDA) levels increased significantly at all exposure periods with increasing concentrations of LAE. Moreover, the effects of LAE on Tubifex tubifex were demonstrated by the establishment of potency index, integrated biomarker response (IBR) and biomarker response index (BRI) assessment. These findings suggest that exposure of Tubifex tubifex to LAE influences the survival of Tubifex tubifex at the acute stage and modifies alterations in oxidative stress enzymes at the sublethal level. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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