Studies on the Urinary Excretion of 17-Ketosteroids by the Domestic Pig1
| Autor: | A.F. Clark, James I. Raeside, Samuel Solomon |
|---|---|
| Rok vydání: | 1965 |
| Předmět: |
endocrine system
medicine.medical_specialty Androsterone Etiocholanolone BOAR urogenital system business.industry Urinary system Urine Excretion Domestic pig chemistry.chemical_compound Endocrinology chemistry Internal medicine polycyclic compounds medicine Ovariectomized rat business hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Endocrinology. 76:427-433 |
| ISSN: | 1945-7170 0013-7227 |
| Popis: | Urines from normal and gonadectomized male and female pigs were analyzed for 17-ketosteroids. Dehydroiosandrosterone, isoandrosterone, androsterone, etiocholanolone, 11-ketoetiocholanolone, 11/3-hydroxy - androsterone and 11β-hydroxyetiocholanolone were isolated from normal boar urine. The level of excretion of the ll-desoxy-17-ketosteroids by the intact boar is higher than that of other species thus far reported. The three ll-oxy-17-ketosteroids were found in the urine of castrated boars and ovariectomized sows. No 17-ketosteroids were found in the urine from normal sows. Androsterone, 11β- hydroxyandrosterone and 11β-hydroxyetiocholanolone were isolated from the urine of pregnant sows. HCG administration resulted in a large increase, while ACTH administration led to a decrease in the daily excretion of the urinary ll-desoxy-17-ketosteroids. From the evidence obtained it was concluded that in the boar the precursors of the ll-desoxy- 17-ketosteroids are elaborated by the testes, and that dehydroisoandros... |
| Databáze: | OpenAIRE |
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