Novel Adsorbents for Hydrophilic Chromatography Based on Silica Gel Covalently Modified with Poly(ethylene glycol)
| Autor: | A. V. Chernobrovkina, Oleg A. Shpigun, Alexander D. Smolenkov, A.S. Popov, G. S. Maksimov |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
chemistry.chemical_classification Chromatography 030102 biochemistry & molecular biology Silica gel Hydrophilic interaction chromatography 010401 analytical chemistry General Chemistry 01 natural sciences 0104 chemical sciences Amino acid 03 medical and health sciences chemistry.chemical_compound Adsorption chemistry Covalent bond PEG ratio Selectivity Ethylene glycol |
| Zdroj: | Moscow University Chemistry Bulletin. 76:75-84 |
| ISSN: | 1935-0260 0027-1314 |
| DOI: | 10.3103/s0027131421010132 |
| Popis: | Novel stationary phases based on aminopropyl silica gel covalently modified with poly(ethylene glycol) (PEG) with different matrix-to-polymer mass ratios are obtained. The chromatographic properties of the adsorbents are studied using the Tanaka test procedure for hydrophilic stationary phases (and by way of example of separating model mixtures of sugars, amino acids, and water-soluble vitamins). It is shown that varying the thickness of the layer of (PEG) not only affects the efficiency but also makes it possible to tailor the selectivity toward polar analytes in the hydrophilic interaction liquid chromatography mode. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink