Direct Probes of 4 nm Diameter Gold Nanoparticles Interacting with Supported Lipid Bilayers
| Autor: | Li Fu, Joel A. Pedersen, Arielle C. Mensch, Laura L. Olenick, Marco D. Torelli, Christopher R. Anderton, Eric S. Melby, Eseohi Ehimiaghe, Robert J. Hamers, Julianne M. Troiano, Franz M. Geiger, Hong-fei Wang, Dehong Hu, Merve Doğangün, Galya Orr, Zihua Zhu, Thomas R. Kuech, Ariane M. Vartanian, Samuel E. Lohse, Stephanie R. Walter, Catherine J. Murphy |
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| Rok vydání: | 2014 |
| Předmět: |
Chemistry
Analytical chemistry Phospholipid Cationic polymerization Nanoparticle Polyelectrolyte Surfaces Coatings and Films Electronic Optical and Magnetic Materials Allylamine chemistry.chemical_compound General Energy X-ray photoelectron spectroscopy Colloidal gold Physical and Theoretical Chemistry Lipid bilayer |
| Zdroj: | The Journal of Physical Chemistry C. 119:534-546 |
| ISSN: | 1932-7455 1932-7447 |
| Popis: | This work presents molecular-level investigations of how well-characterized silica-supported phospholipid bilayers formed from either pure DOPC or a 9:1 mixture of DOPC:DOTAP interact with positively and negatively charged 4 nm gold metal nanoparticles at pH 7.4 and NaCl concentrations ranging from 0.001 to 0.1 M. Second harmonic generation (SHG) charge screening measurements indicate the supported bilayers carry a negative interfacial potential. Resonantly enhanced SHG measurements probing electronic transitions within the gold core of the nanoparticles show the particles interact irreversibly with the supported bilayers at a range of concentrations. At 0.1 M NaCl, surface coverages for the particles functionalized with the negatively charged ligand mercaptopropionic acid (MPA) or wrapped in the cationic polyelectrolyte poly(allylamine) hydrochloride (PAH) are estimated from a joint analysis of QCM-D, XPS, AFM, and ToF-SIMS to be roughly 1 × 107 and 1 × 1011 particles cm–2, respectively. Results from com... |
| Databáze: | OpenAIRE |
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