Synthesis of [14C]labelled pyrano[3,4-b]-and thiopyrano[3,4-b]indoles, and indeno[2,1-c]pyran derivatives

Autor:	D. R. Hicks, E. S. Ferdinandi, P. Raman, W. Verbestel
Rok vydání:	1978
Předmět:	Indole test Gramine Stereochemistry Organic Chemistry Ring (chemistry) Biochemistry Analytical Chemistry chemistry.chemical_compound chemistry Pyran Drug Discovery Tryptophol Radiology Nuclear Medicine and imaging Indene Spectroscopy
Zdroj:	Journal of Labelled Compounds and Radiopharmaceuticals. 14:411-425
ISSN:	0362-4803
DOI:	10.1002/jlcr.2580140315
Popis:	The synthesis of four structurally similar [14C]labelled compounds having a novel heterocylic ring system is described. Three compounds with a tetrahydropyrano (or thiopyrano) indole nucleus were prepared from suitably substituted [14C]tryptophols and were labelled in the pyrano or thiopyrano ring. The preparation of the [14C]tryptophol intermediates from the appropriate gramine is described. The synthesis of the fourth compound, a tetrahydroindenopyran derivative labelled in the indene nucleus, involved a novel preparation of [14C]indene.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f326233a754f5e3b192e642ac93817ba https://doi.org/10.1002/jlcr.2580140315 Zobrazit plný text záznamu Plný text