Recent advances of scanning electrochemical microscopy and scanning ion conductance microscopy for single-cell analysis
| Autor: | Wenxuan Fu, Tong Zhu, Junjie Zhang, Fei Li, Jinxin Lang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Materials science
Nanotechnology 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Cell morphology 01 natural sciences 0104 chemical sciences Analytical Chemistry Characterization (materials science) Scanning electrochemical microscopy Scanning probe microscopy Membrane Single-cell analysis Electrochemistry Scanning ion-conductance microscopy Surface charge 0210 nano-technology |
| Zdroj: | Current Opinion in Electrochemistry. 22:178-185 |
| ISSN: | 2451-9103 |
| DOI: | 10.1016/j.coelec.2020.06.001 |
| Popis: | Single-cell analysis is important for understanding fundamental biological processes and mechanisms. Scanning electrochemical microscopy and scanning ion conductance microscopy as two kinds of scanning probe microscopy, with high temporal and spatial resolutions as well as in situ and noninvasive characterization capabilities, emerge as strong tools for single-cell analysis. In this review, we introduce the latest advances of scanning electrochemical microscopy and scanning ion conductance microscopy for single-cell analysis, including characterizations of cell morphology dynamics, membrane properties and mechanics, and monitoring cell surface charge, extracellular pH, and intracellular substances. |
| Databáze: | OpenAIRE |
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