Facile Synthesis of Ultrasmall, Highly Stable, and Biocompatible Gold Nanoparticles Stabilized with Lipoic Acid: Cytotoxicity and Structural Characterization
| Autor: | Betania Sánchez-Santamaria, Delfino Cornejo-Monroy, I. Olivas-Armendáriz, Erwin Adán Martínez-Gómez, Victor M. Castaño, J.S. Arias-Cerón, Alfredo Villanueva-Montellano |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
General Engineering
02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics Biocompatible material 01 natural sciences 0104 chemical sciences symbols.namesake Lipoic acid chemistry.chemical_compound Colloid chemistry Colloidal gold symbols General Materials Science MTT assay 0210 nano-technology Raman spectroscopy Spectroscopy Cytotoxicity Nuclear chemistry |
| Zdroj: | Nanotechnologies in Russia. 14:607-612 |
| ISSN: | 1995-0799 1995-0780 |
| DOI: | 10.1134/s199507801906003x |
| Popis: | Using the colloidal method, and lipoic acid as a stabilizer, ultrasmall gold nanoparticles with an average size of 2.5 nm were synthesized. They are highly stable, have COOH functional groups, at concentrations lower than 100 μg/mL are non-cytotoxic, and the synthesis route is simple and economical. UV–Vis, FT-IR, Raman, and TEM spectroscopy were used to analyze their stability, composition and morphology. Furthermore, the cytotoxicity of the gold nanoparticles was evaluated by MTT assay. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink