Serum Contents of the Free Forms of α1-Microglobulin and Ulinastatin: Relation to Diseased States in Patients with Mood Disorders
| Autor: | Jun Uegaki, Tadahiro Shikimi, Koichi Kaku, Takuji Inagaki, Hiroshi Ishino, Shuji Takaori, Haruo Seno |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
Beta-2 microglobulin Urinary system Hamilton Rating Scale for Depression Ulinastatin medicine.disease Gastroenterology humanities Developmental psychology Psychiatry and Mental health chemistry.chemical_compound Neuropsychology and Physiological Psychology Mood chemistry Mood disorders Internal medicine medicine In patient Psychology Biological Psychiatry Depression (differential diagnoses) |
| Zdroj: | Neuropsychobiology. 43:145-149 |
| ISSN: | 1423-0224 0302-282X |
| DOI: | 10.1159/000054883 |
| Popis: | We have found previously that the relationship between the urinary contents of α1-microglobulin (α1M) and ulinastatin (UT) in patients with mood disorder differs from that of age-matched healthy subjects. However, it has yet to be determined whether or not the difference in the relation correlates with the contents of the free forms of α1M and UT in serum and whether changes in the existing forms of α1M and UT in serum reflect the actual disease states. The relation between serum contents of the free forms of α1M and UT in 10 patients with mood disorders was different from that of 17 age-matched healthy subjects. The regression plot between scores of the Hamilton Rating Scale for Depression and ratios of the free form content to total content (F/T ratio) of UT was more informative on the depressive state than that of α1M. The F/T ratios of UT may afford a useful objective index in monitoring the diseased state of a patient with mood disorder. |
| Databáze: | OpenAIRE |
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