Identification of Two Phenanthrene Derivatives from Australasian Allied Species in Genus Dendrobium
| Autor: | Yurika Tsurumaki, Aoi Miyamoto, Susumu Kitanaka, Saki Kitamura, Tomoko Takamiya, Yukiko Fujiwara, Megumi Furukawa, Shunichiro Suzuki, Yoshifumi Matsuo, Dai Hirose, Kento Murase, Keiichi Matsuzaki, Mitsuko Makino, Hiroshi Iijima, Ryohei Matsumoto, Tomohisa Yukawa, Yuka Kaiho, Tomomi Machida, Nao Shioda, Mayumi Sone |
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| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Chemical and Pharmaceutical Bulletin. 66:642-650 |
| ISSN: | 1347-5223 0009-2363 |
| Popis: | Genus Dendrobium (Orchidaceae) contains numerous species. Phylogenetic analyses based on morphological characteristics and DNA sequences indicated that this genus is divided into two major groups: Asian and Australasian clades. On the other hand, little is known about the phytochemical differences and similarities among the species in each clade. In this study, we selected 18 Dendrobium species (11 from the Asian clade and 7 from the Australasian clade) and constructed HPLC profiles, arrays composed of relative intensity of the chromatographic peaks. Next, orthogonal partial least square discriminant analysis (OPLS-DA) was applied to the profile matrix to classify Dendrobium species into the Asian and Australasian clades in order to identify the peaks that significantly contribute to the class separation. In the end, two phenanthrenes, 4,9-dimethoxyphenanthrene-2,5-diol 1 and 1,5-dimethoxyphenanthrene-2,7-diol 2, which contributed to the class separation, were isolated from the HPLC peaks. The existence of 2 was limited to the genetically related Australasian species. |
| Databáze: | OpenAIRE |
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