An efficient method to access 2-substituted benzimidazoles under solvent-free conditions

Autor:	Threshia S. Malcolm, Ping Lan, Benjamin D. Stevens, F. Anthony Romero, Dariusz Wodka, Gergely M. Makara
Rok vydání:	2008
Předmět:	chemistry.chemical_classification Benzimidazole chemistry.chemical_compound Solvent free Nucleophile chemistry Organic Chemistry Drug Discovery Organic chemistry Phenols Biochemistry Alkyl
Zdroj:	Tetrahedron Letters. 49:1910-1914
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2008.01.100
Popis:	An expeditious method to access 2-substituted benzimidazoles was developed. Both aromatic (phenols, anilines, and thiophenols) and alkyl nucleophiles (amines and thiols) react with 2-methylsulfonyl benzimidazole under solvent-free conditions to generate a variety of 2-substituted benzimidazoles.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f2a4ceeff2e95857a9c32903c2353518 https://doi.org/10.1016/j.tetlet.2008.01.100 Zobrazit plný text záznamu Full Text from ScienceDirect