Three new oxylipins from an Okinawan marine sponge Plakortis sp

Autor:	Naonobu Tanaka, Jun'ichi Kobayashi, Taishi Kusama, Jane Fromont, Miki Asai
Rok vydání:	2015
Předmět:	chemistry.chemical_compound Sponge chemistry biology Stereochemistry Organic Chemistry Drug Discovery Cyclohexanone Oxylipin biology.organism_classification Biochemistry Two-dimensional nuclear magnetic resonance spectroscopy Nmr data
Zdroj:	Tetrahedron Letters. 56:1388-1391
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2015.01.137
Popis:	Three new oxylipins, manzamenone P ( 1 ), 6′- O -methylmanzamenone K ( 2 ), and 6′- O -ethylmanzamenone K ( 3 ), were isolated from an Okinawan marine sponge Plakortis sp. Manzamenone P ( 1 ) is a unique oxylipin possessing two long acyl chains and a novel core unit consisting of spiro-bonded cyclohexanone and β-keto-γ-lactone rings. The structures of 1 – 3 were elucidated on the basis of spectroscopic evidences including 2D NMR and FABMS/MS spectra as well as a comparison of DFT calculated NMR data with those experimental data.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f29ceb5cf302499cb00e93d06e19d638 https://doi.org/10.1016/j.tetlet.2015.01.137 Zobrazit plný text záznamu Full Text from ScienceDirect