Automated batch scale-up of microwave-promoted Suzuki and Heck coupling reactions in water using ultra-low metal catalyst concentrations

Autor:	Michael J. Collins, Riina K. Arvela, Nicholas E. Leadbeater
Rok vydání:	2005
Předmět:	Chemical engineering Chemistry Heck reaction Organic Chemistry Drug Discovery SCALE-UP Organic chemistry Metal catalyst Biochemistry Microwave Catalysis
Zdroj:	Tetrahedron. 61:9349-9355
ISSN:	0040-4020
DOI:	10.1016/j.tet.2005.07.063
Popis:	Representative Suzuki and Heck couplings in water using ultra-low catalyst concentrations have been scaled-up using an automated batch stop-flow microwave apparatus. Our scale-up methodology shows proof of concept and is easy, fast and cheap to run.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f27284ec308e0619cac9b7b3b95c95fc https://doi.org/10.1016/j.tet.2005.07.063 Zobrazit plný text záznamu Full Text from ScienceDirect