Popis: |
Twenty four male rats weighing between 120-130 g were randomly assigned into four groups. Group A was fed normal diet; Group B, C and D were fed hypercholesterolemic diet (i.e. 20% fat + 1% cholesterol) for two weeks to establish hypercholesterolemia. Thereafter, Group B were maintained on hyper diet, while C and D were fed 5% and 10% Sesamum indicum oil supplemented diet for four weeks. Plasma was collected and analyzed for the activity of alkaline phosphatase (ALP) and concentrations of urea, creatinine, sodium, and potassium. The kidney was removed, decapsulated, weighed, homogenized, centrifuged and ALP activity was determined inthe supernatant. Significant increase (P |