| Autor: |
Miranda Tsai, Susan Wagner, Amanda Clarke, Michael Mayo, Richard D. Moore, Robert A. Holt, Mirunali Balasundaram, Sarah A. Munro, Didi Leung |
| Rok vydání: |
2010 |
| Předmět: |
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| Zdroj: |
Clinical Governance: An International Journal. 15:102-112 |
| ISSN: |
1477-7274 |
| DOI: |
10.1108/14777271011035040 |
| Popis: |
PurposeThe purpose of this paper is to discuss a practical approach taken by utilizing the non‐conformance/event management and failure investigation (FI) system to formally troubleshoot an actual process failure observed in the sequencing facility.Design/methodology/approachIn this study the authors describe how the cause for the poor quality sequence data, as indicated from the quality score, involving high molecular weight follicular lymphoma DNA samples for a study of tumor‐associated genome rearrangements was successfully identified and confirmed through the application of a well structured FI process.FindingsThrough this FI process the underlying causes were effectively identified, immediate corrective actions were executed and a preventative action to avoid or minimize reoccurrences was also implemented and monitored for effectiveness.Originality/valueThis paper establishes that by applying a systematic, documented FI process the underlying causes of a process failure in an organization can be effectively identified and appropriate corrective and preventative actions can be successfully adopted. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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