Antiatherogenic action of corn oil in experimental atherosclerosis
| Autor: | M K Evstigneeva, A G Sdvigova, Torkhovskaia Ti, Khalilov Em, Zh I Kliuchnikova, Iu M Lopukhin |
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| Rok vydání: | 1992 |
| Předmět: |
Experimental atherosclerosis
chemistry.chemical_classification Cholesterol diet Aorta Chemistry Cholesterol Therapeutic effect food and beverages General Medicine General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound medicine.artery medicine lipids (amino acids peptides and proteins) Food science Corn oil Lipoprotein cholesterol Polyunsaturated fatty acid |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 113:637-640 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | Therapeutic effect of corn oil was studied in rabbits with alimentary atherosclerosis. Corn oil was administered (2 ml/kg, 30 days) after the completion of cholesterol diet unlike studies, where they were administered simultaneously. Total cholesterol, apoB-lipoprotein cholesterol and triglycerides decreased more intensively in rabbits fed by corn oil than in control group. No changes in high-density lipoprotein cholesterol were observed. The most pronounced effect was noted in aorta morphological analysis: an aorta damage degree was 4.8% as compared with 52.9% in the control group. The results show that available plant oils with omega-6 polyunsaturated fatty acids (PUFA), in particular corn oil, may as well as omega-3 PUFA be used as the base for antiatherogenic preparations. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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