Metalloprotein-Catalyzed Click Reaction for In Situ Generation of a Potent Inhibitor
| Autor: | Yasunobu Yamashita, Takayoshi Suzuki, Yoshinori Suzuma, Remy Narozny, Shusaku Uchida, Yuka Miyake, Yukihiro Itoh, Hidehiko Kodama, Takashi Kurohara, Yutaro Hanatani |
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| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
In situ 010405 organic chemistry TheoryofComputation_GENERAL General Chemistry 010402 general chemistry behavioral disciplines and activities 01 natural sciences Combinatorial chemistry Catalysis 0104 chemical sciences chemistry otorhinolaryngologic diseases Metalloprotein Click chemistry InformationSystems_MISCELLANEOUS human activities |
| Zdroj: | ACS Catalysis. 10:5383-5392 |
| ISSN: | 2155-5435 |
| DOI: | 10.1021/acscatal.0c00369 |
| Popis: | In situ click chemistry has great potential for identifying enzyme inhibitors. However, conventional in situ click chemistry provides extremely low yields of the products, making it incompatible wi... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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