Biodegradable self-reinforced polyglycolide (SR-PGA) composite rods coated with slowly biodegradable polymers for fracture fixation: strength and strength retention in vitro and in vivo

Autor:	Pertti Törmälä, Matti Mero, Jukka Mikkola, Jarkko Vasenius, Pentti Rokkanen, Seppo Vainionpää, K. Vihtonen
Rok vydání:	1989
Předmět:	Osteosynthesis Materials science genetic structures Polyglycolide Composite number Biophysics Biodegradable polymer Rod chemistry.chemical_compound Distilled water chemistry In vivo Fracture fixation sense organs Composite material
Zdroj:	Clinical Materials. 4:307-317
ISSN:	0267-6605
DOI:	10.1016/0267-6605(89)90011-5
Popis:	The strength retention of coated and uncoated self-reinforced polyglycolide (SR-PGA) rods was evaluated after immersion in distilled water at 37°C and after implantation in the subcutis of rabbit. Slowly biodegradable coatings improved only the in-vitro strength retention of SR-PGA osteosynthesis implants. In the in-vivo environment the rods lost their strength in 5–6 weeks, and there was no significant difference in the strength retention between coated and uncoated rods. The SR-PGA rods lost their strength considerably faster in vivo than in vitro.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f205ffcecae942af44b1809a4593d2e4 https://doi.org/10.1016/0267-6605(89)90011-5 Zobrazit plný text záznamu