Cranberry (Vaccinium macrocarpon) et infections urinaires: étude et revue de la littérature

Autor: Albert Sotto, H. Botto, Gisèle Bourg, J.-P. Lavigne
Rok vydání: 2007
Předmět:
Zdroj: Pathologie Biologie. 55:460-464
ISSN: 0369-8114
DOI: 10.1016/j.patbio.2007.07.005
Popis: Cranberries (Vaccinium macrocarpon) have long been the focus of interest for their beneficial effects in preventing urinary tract infections. Among cranberry compounds, a group of proanthocyanidins (PACs) with A-type linkages were isolated which exhibit bacterial anti-adhesion activity against uropathogenic Escherichia coli strains. These PAC inhibit P-fimbriae synthesis and induce a bacterial deformation. This activity was demonstrated on both antibiotic susceptible and resistant bacteria. This review focused on the last discoveries in the knowledge of cranberry effects.
Databáze: OpenAIRE