Correlation of Fine Needle Aspiration Biopsy and Dynamic Contrast-Enhanced 3D Magnetic
| Autor: | Virginia M. Herrmann, William H. Perman, Brian T. Collins, Elisabeth Heiberg |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
Histology Percutaneous medicine.diagnostic_test business.industry Mammary gland Magnetic resonance imaging General Medicine medicine.disease Pathology and Forensic Medicine Fine-needle aspiration medicine.anatomical_structure Cytopathology Biopsy medicine Carcinoma Radiology Breast disease business |
| Zdroj: | Acta Cytologica. 43:158-162 |
| ISSN: | 1938-2650 0001-5547 |
| DOI: | 10.1159/000330970 |
| Popis: | OBJECTIVE: To correlate and assess the utility of dynamic contrast-enhanced three-dimensional gadolinium-enhanced magnetic resonance imaging (Gd-3DMRI) and fine needle aspiration biopsy (FNAB) findings in patients with suspected breast disease. STUDY DESIGN : Beginning in 1993, all patients who underwent percutaneous FNAB of the breast and had concurrent Gd-3DMRI evaluation of the breast were selected for this study. Findings for FNAB and Gd-3DMRI were stratified into two categories, positive and negative. Subsequent clinical management decisions, which included surgical intervention and/or clinical follow-up, were recorded for all patients. RESULTS : There were 69 FNABs in 59 patients with corresponding Gd-3DMRI evaluation. A positive result by both FNAB and Gd-3DMRI was found in 15 of 18 malignant cases. FNAB missed one case, and Gd-3DMRI missed two, arid each of these was thought to be technical. Combining the methods yielded 100% sensitivity. False positive results on Gd-3DMRI (17 cases) were all confirmed to be benign by FNAB and subsequent tissue evaluation. All 32 cases with combined negative results by FNAB and Gd-3DMRI demonstrated a benign process, yielding a specificity of 100% (32/32). CONCLUSION: Our combined testing modalities showed a high degree of specificity and good sensitivity. FNAB used with dynamic contrast-enhanced Gd-3DMRI can contribute valuable information for physicians treating patients with suspected breast abnormalities. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|