An engineered β-galactosidase with improved stability and cross-correction for the potential treatment of GM1 Gangliosidosis via AAV gene therapy

Autor:	Charu Reddy, Ouma Onguka, Jacob Artz, Christopher Schmitt, Adam Grossman, Swetha Santosh, Oluwayomi Akinkugbe, Victoria Wong, Kahsay Gebretsadik, Faezeh Sedighi, Jinyan Tang, Elizabeth Del Greco, Grace S. Lee, Nikki Kruse, Chinping Chng, Da Duan, William C. Hallows, Joseph C. Chen, Hassibullah Akeefe, Adam P. Silverman, Gjalt Huisman
Rok vydání:	2023
Předmět:	Endocrinology Endocrinology Diabetes and Metabolism Genetics Molecular Biology Biochemistry
Zdroj:	Molecular Genetics and Metabolism. 138:107285
ISSN:	1096-7192
DOI:	10.1016/j.ymgme.2022.107285
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f1c904fd0acaab184cf602a224ece715 https://doi.org/10.1016/j.ymgme.2022.107285 Zobrazit plný text záznamu Full Text from ScienceDirect