Preparation and benzoylation of 3-hydroxy-2,3,5,5-tetramethyl-1-pyrroline 1-oxide (3-hydroxy-2,3,5,5-tetramethyl-4,5-dihydro-3H-pyrrole 1-oxide)

Autor:	Alexander R. Forrester, Neil J. Gibson, Charles Brown
Rok vydání:	1995
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Benzoyl chloride chemistry Stereochemistry Yield (chemistry) Butanone Oxide Pyrroline Medicinal chemistry Tricyclic Pyrrole
Zdroj:	Journal of the Chemical Society, Perkin Transactions 1. :507
ISSN:	1364-5463 0300-922X
Popis:	Treatment of 2,3,5,5-tetramethyl-3-hydroxy-1-pyrroline 1-oxide 6, prepared from butanone in six steps, with benzoyl chloride under Schotten–Baumann conditions leads to an unprecedented dimerisation to give a spiro, tricyclic N-benzoyloxypyrrolidine in good yield.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f1c51f4825d6a2541daacdf509d8c920 https://doi.org/10.1039/p19950000507 Zobrazit plný text záznamu