Abstract 60: Diverging Time Trends Of Gender-specific Ischemic Stroke Incidence - 10-year-analysis Of A State-wide Registry In Germany
| Autor: | Jan Schaefer, Ferdinand O Bohmann, Björn Misselwitz, Christian Foerch |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Stroke. 53 |
| ISSN: | 1524-4628 0039-2499 |
| Popis: | Introduction: The incidence of ischemic stroke (IS) was previously expected to rise among countries with an ageing population. Lately, several studies from developed countries have reported a decline in certain cohorts. Whether this applies to all genders, however, is uncertain along with limited data on the temporal development in incidence, treatment, and recovery. Methods: We analyzed a prospective stroke inpatient quality assurance registry of the federal state of Hesse, Germany. Recruitment of all patients with a final diagnosis of ischemic stroke at hospital discharge (ICD10: I63) is mandatory by law. Stroke incidence rates were calculated based on census data of all inhabitants and stratified according to age. Results: Between 2010 and 2019 141,277 patients were included, 73,770 (52.2%) male and 67.507 (47.8%) female. Overall, the incidence of IS was 228/100,000 in 2010 and 226/100,000 in 2019 (OR 0.99; 95%-CI 0.96 to 1.02; p=0.50). For men, the incidence increased continuously from 236/100,000 to 245/100,000, in women it decreased from 220/100,000 to 208/100,000. After adjusting for age, the odds ratio for IS between men and women was 1.40 in 2010 (95%-CI 1.35 to 1.44; p Discussion: Over the last decade, the overall incidence of IS has declined predominantly in the female population. Contrarily, for men the incidence has risen by about 4% with a steeper increase of 17% in males aged 45-59 years. This finding could be explained by higher rates of prior strokes, arterial hypertension and diabetes in men compared to women. Notably, the high rate of recurrent strokes in men provides a cautionary tale for effective secondary prevention. |
| Databáze: | OpenAIRE |
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