Physical activity in cardiovascular disease prevention in patients with HIV/AIDS

Autor: Gregory A. Hand, G. William Lyerly, Jason R. Jaggers, Wesley D. Dudgeon
Rok vydání: 2009
Předmět:
Zdroj: Current Cardiovascular Risk Reports. 3:288-295
ISSN: 1932-9563
1932-9520
DOI: 10.1007/s12170-009-0044-5
Popis: The introduction of highly active antiretroviral therapy (HAART) has both extended life expectancy and reduced morbidity in people living with HIV/AIDS (PLWHA). These changes have resulted in the emergence of cardiovascular disease (CVD) and associated risk factors as a threat to the health of PLWHA. The major components of CVD risk associated with HIV infection include HIV, HAART, nonmodifiable factors such as genetics or environment, and modifiable risk factors such as inactivity and poor diet. Physical activity has been shown to be beneficial in reducing the risk of CVD through its effect on numerous modifiable risk factors, including functional aerobic impairment, dyslipidemia and insulin resistance, obesity, and atherosclerotic inflammation. A growing body of evidence indicates that exercise has similar benefits for these modifiable CVD risk factors that are exacerbated in PLWHA.
Databáze: OpenAIRE