Efficacy of Oral Low-Dose Tretinoin (all-trans-Retinoic Acid) in Lichen planus
| Autor: | W. Bollag, F. Ott, J. M. Geiger |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Drug
medicine.medical_specialty Chemotherapy integumentary system business.industry medicine.medical_treatment media_common.quotation_subject Low dose Complete remission All trans Retinoic acid Dermatology stomatognathic diseases chemistry.chemical_compound stomatognathic system chemistry Tretinoin Oral administration medicine skin and connective tissue diseases business medicine.drug media_common |
| Zdroj: | Dermatology. 192:334-336 |
| ISSN: | 1421-9832 1018-8665 |
| Popis: | Background: Retinoids were shown to be effective in the treatment of both oral and cutaneous forms of lichen planus. Objective: Confirm the beneficial effect of low doses of oral tretinoin in lichen planus. Methods: Eighteen patients with lichen planus were treated in an open study for up to 19 months. Efficacy and safety data were recorded. Results: Complete remission was observed in 13 (72%) and marked improvement in 4 (22%) out of 18 patients. Six patients showed moderate and 12 had no side effects. Conclusion: Tretinoin is a valuable drug when given at low doses to patients with lichen planus who failed to respond to other therapies. |
| Databáze: | OpenAIRE |
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