β-lactamase production in Provotella and in vitro susceptibilities to selected β-lactam antibiotics
| Autor: | F. Mory, C Vouillot, A. Sedallian, S. Bland, Josette Behra-Miellet, Luc Dubreuil |
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| Rok vydání: | 2003 |
| Předmět: |
Microbiology (medical)
Cefotaxime medicine.drug_class Cephalosporin General Medicine biochemical phenomena metabolism and nutrition Biology Cefpodoxime biology.organism_classification Microbiology stomatognathic diseases Infectious Diseases Ticarcillin polycyclic compounds medicine Prevotella Pharmacology (medical) Cefixime Cefuroxime Antibacterial agent medicine.drug |
| Zdroj: | International Journal of Antimicrobial Agents. 21:267-273 |
| ISSN: | 0924-8579 |
| DOI: | 10.1016/s0924-8579(02)00352-7 |
| Popis: | This study looked for beta-lactamase production in 100 Prevotella isolates. MICs were determined for amoxycillin, ticarcillin, amoxycillin+clavulanate, cephalothin, cefuroxime, cefixime, cefpodoxime and cefotaxime using the reference agar dilution method (standard M11 A4, NCCLS). Beta-lactamase activity was detected in 58 of the 100 isolates, 24 of 46 black-pigmented Provotella and 34 of 54 non-pigmented Prevotella. All beta-lactamase-negative strains were susceptible to all beta-lactam antibiotics with the exception of cefuroxime and cefixime. Overall, resistance rates of Prevotella strains were lower for ticarcillin (8%) and celefotaxime (12%) than for the other cephalosporins. All Prevotella isolates were susceptible to amoxycillin and were all inhibited by 2 mg/l or less amoxycillin [corrected]. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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