Adhäsionen und ihre Prävention in der gynäkologischen Chirurgie: Standortbestimmung und aktueller Konsensus basierend auf den Ergebnissen von vier Workshops

Autor: R. L. De Wilde, Matthias Korell, S. Rimbach, Hans-Rudolf Tinneberg
Rok vydání: 2004
Předmět:
Zdroj: Geburtshilfe und Frauenheilkunde. 64:891-899
ISSN: 1438-8804
0016-5751
DOI: 10.1055/s-2004-821239
Popis: The problem of postoperative adhesions has gained a new topicality by the recent publication of epidemiological data on adhesion associated consequences and complications, not available so far. At the same time, new methods seem to offer a realistic chance of adhesion risk reduction. As evidence-based recommendations are lacking so far, a definition for a more general orientation in the form of a consensus is presented as a first step, based on the results of four roundtable workshops held by the authors and with the contributions from collegues of 35 German hospitals. With respect to the importance of adhesions it can be stated that a large spectrum of gynaecologic operations, open as well as laparoscopic, induce adhesions to a relevant extent. This is the reason behind the request for efficient adhesion prevention, which is currently met best by the application of so-called barrier products. On the one hand, viscous substances with local effect are available. For the newer polyethylenglycol and hyaluronic acid products data are still lacking, but the efficacy of regenerated oxydized cellulose is well investigated. On the other hand, a possible advantage with an effect throughout the entire peritoneal cavity seems to exist for icodextrin. The substance has proven to be safe in contrast to several other products already withdrawn from the market and shows promising first study data with respect to its anti-adhesive efficacy.
Databáze: OpenAIRE