Light emitting diode mediated photobiomodulation therapy improves orthodontic tooth movement and miniscrew stability: A randomized controlled clinical trial

Autor: Gökhan Türker, Enis Güray, Zekeriya Taşdemir, Tancan Uysal, Abdullah Ekizer
Rok vydání: 2016
Předmět:
Zdroj: Lasers in Surgery and Medicine. 48:936-943
ISSN: 0196-8092
DOI: 10.1002/lsm.22516
Popis: Background and Objectives The aim of this study was to evaluate the effects of light-emitting diode-mediated-photobiomodulation therapy (LPT) on the stability of miniscrews, rate of orthodontic tooth movement, and interleukin-1β levels in gingival and peri-implant crevicular fluid. Materials and Methods This study was a double blind, randomized placebo/control matched pairs clinical trial to test the efficacy of LPT. This split-mouth design study consisted of 20 patients (13 girls, 7 boys). The eligibility criteria included patients who had extraction of maxillary first premolars. Mini-screws were placed between maxillary first molars and second premolars on both sides as anchorage units. LPT was applied with an energy density of 20 mW/cm2 over a period of 21 successive days (20 minutes per day) over the movement of canine teeth on the test side and using a pseudo application on the placebo side. The main outcome of this study was to assess effect of LPT on the rate of orthodontic tooth movement. The secondary outcomes were measuring stability of miniscrews and interleukin-1β levels in gingival and peri-implant crevicular fluid after LPT. Randomization was accomplished with random LPT application side selection by coin toss. Measurements were made by blinding clinicians. Blinding of the patients was achieved using the same LPT device on both sides but irradiating only one side. For statistical comparison, paired samples t-test and one-way analysis of variance (ANOVA) were used at P
Databáze: OpenAIRE