Production of alpha heavy chain mRNA in mucosal and lymphoid tissue of various strains of mice

Autor: J D Cooley, A O Anderson, M Vahey, M L M Pitt
Rok vydání: 1990
Předmět:
Zdroj: Advances in Mucosal Immunology ISBN: 9789401073233
DOI: 10.1007/978-94-009-1848-1_86
Popis: C3H/HeJ mice, which are non-responsive to lipopolysaccharide (LPS), elicit higher IgA responses, including increased splenic indirect plaque-forming cell and serum antibody responses to orally administered antigen compared to the syngeneic LPS responsive C3H/HeN mice (1). These elevated IgA responses are thought to be due to induction of T helper cell activity in mucosal lymphoid tissue (2).
Databáze: OpenAIRE